The Brazilian opened the scoring for Luis Enrique's men midway through the first half, but Messi stole the show by bagging a hat-trick on his 300th Liga appearance before substitute Luis Suarez finished off the 5-0 thrashing with an acrobatic bicycle kick.
Neymar, who has been a Camp Nou player for almost two years now, has explained the extent of his bond with the four-time Ballon d'Or winner and insists his penalty miss in midweek against Villarreal has not affected him at all.
"Some things come easy to Barca and we just put in one of our best performances," the 23-year-old told Canal Plus.
"I'm very happy with the result. The other day I missed a penalty but these things happen. For me it is an honour to play alongside Messi, Luis Suarez and Pedro. Messi is the best friend I have, both at Barca and away from the football pitch."
Barcelona are back in action next Saturday at home to Malaga before they take a trip to Manchester City in the first leg of their Champions League last-16 tie.